The present study is conducted to evaluate the antibacterial and wound healing activities of leaves of plants Rosa indica (Rosaceae) by Invitro and in vivo model studies. Studies on the antibacterial activity of 70% ethanol and methanol extract of Rosa indica (pink rose, orange rose) leaves were conducted using agar well diffusion method and on wound healing activity. 70% ethanol and methanol extract of Rosa indica leaves (pink rose, orange rose) conducted using Excision wound model . The micro organism used were Staphylococcus aureus,Bacillus subutilis, Escheria coli and animals used were Albino rat (wistar strain). The results showed that 5mg/ml showed moderate zone of inhibition against staphylococcus aureus and Escheria coli, maximum zone of inhibition were produced against them at 20mg/ml. Bacillus subtilis was resistant to both ethanolic and methanolic extracts.(Table1). Both ethanolic and methanolic extracts of orange rose variety were only effective against staphylococcus aureus at 20mg/ml and In wound healing study the 5mg/ml ethanolic extract of leaves of pink rose has highest wound healing activity .Also 5mg/ml methanolic extract of leaves of pink rose has remarkable wound healing activity in compare to control and standard.On the other hand 5mg/ml ethanolic extract of leaves of orange rose has better wound healing activity than standard povidone iodine.The above result revealed that the ethanolic pink rose leaves extract has remarkable anti bacterial and wound healing potency and appear to justify the traditional use of Rosa indica..
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